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Joey Loperfido Replaces Anthony Santander On Blue Jays’ Playoff Roster

October 17, 2025 by MLB Trade Rumors

Major League Baseball has officially approved the substitution of Joey Loperfido for Anthony Santander on the Blue Jays’ playoff roster. Manager John Schneider told reporters (including Ben Nicholson-Smith of Sportsnet) this evening that Santander was dealing with back stiffness. His season is over.

Teams set their postseason rosters at the beginning of each series. They can only make changes mid-series in the event of an injury. A player removed midway through a series is ineligible for the following series if his team advances, so Santander could not participate in the World Series if the Jays come back to beat the Mariners.

Injuries essentially ruined Santander’s first season in Toronto. He was out between the end of May and the middle of September with a left shoulder issue. He didn’t return until the final week of the regular season. Santander has appeared in five of the Jays’ seven postseason games. He missed Game 2 of the ALCS with lower back soreness. Santander returned to the lineup for Game 3 but was replaced by Myles Straw as a defensive substitute in the fifth inning. He finishes his postseason with a 3-15 showing with a pair of runs batted in.

While Davis Schneider drew into the lineup when Santander was out for Game 2, it’s Isiah Kiner-Falefa who picks up the extra playing time tonight. He’s in at second base and batting eighth against Luis Castillo. That pushes Ernie Clement to third base and Addison Barger from the hot corner to right field.

The Jays have carried the same 13 position players for their Division Series and the ALCS. Loperfido had been inactive for both series despite hitting .333/.379/.500 across 41 games during the regular season. He was the only real candidate to join the roster as a left-handed bench bat in Santander’s place. Bo Bichette and Ty France are injured and weren’t ready to go for the beginning of the series. Leo Jiménez finished the season on the Triple-A injured list, leaving light-hitting outfielder Jonatan Clase (who spent the entire second half in Triple-A) as the only other healthy position player on the 40-man roster.

Mitch Bannon and Ken Rosenthal of The Athletic first reported that Santander would be removed from the roster. Nicholson-Smith was first to confirm that Loperfido would be the replacement.

Filed Under: Blue Jays

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